CONGENITAL ANOMALIES AMONG INFANTS OF DIABETIC MOTHERS

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Congenital Anomalies among Infants of Diabetic Mothers

is two to five times greater in infants of diabetic mothers than in other infants. Poor glycemic control in the first trimester during organogenesis is thought to be the major reason for congenital malformations (1). The most frequently seen types of malformations in infants of diabetic mothers involve the cardiovascular, skeletal, central nervous, gastrointestinal and genitourinary systems, wi...

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Congenital malformations in infants of diabetic mothers.

DURING the last two decades the outcome of pregnancy in the diabetic has improved greatly. In the Royal Maternity Hospital, Belfast, for example, the total fetal loss and perinatal mortality during the years 1972-78 have been 4.3 and 3.2 per cent respectively, whereas in earlier years figures well in excess of 10 per cent were common everywhere. In view of this the contribution of congenital ma...

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CONGENITAL HEART DISEASE Cardiovascular malformations in infants of diabetic mothers

Objective: To compare the prevalence at live birth and the spectrum of cardiovascular malformations in infants born to diabetic mothers with pre-existing diabetes with that in infants of non-diabetic mothers. Design: Prospective study of all live births in the resident population of one health region, with recording of details of the outcome of all pregnancies of women with pre-existing diabete...

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Infants of diabetic mothers.

9 Grodsky, G. M., and Forsham, P. H.: An immunochemical assay of total extractable insulin in man. J. Clin. Invest. 39:1070, i960. 10 Field, J. B., and Woodson, M. L.: Studies on the circulating insulin inhibitor found in some diabetic patients exhibiting chronic insulin resistance. J. Clin. Invest. 38:551, 1959. 11 Mitchell, M. L.: Interaction of radioinsulin with serum proteins in vitro and w...

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Infants of diabetic mothers.

Advances in the management of the mother with diabetes have reduced the rate of morbidity and mortality for her infant. Aggressive control of maternal glycemic status is warranted, because most morbidities are epidemiologically and pathophysiologically closely linked to fetal hyperglycemia and hyperinsulinemia. The burgeoning public health problem of overweight and obesity in children will like...

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ژورنال

عنوان ژورنال: Journal of Ankara Medical School

سال: 2002

ISSN: 1300-5464

DOI: 10.1501/jms_0000000076